Indication for Liver Transplantation in Children

Liver transplantation is the gold standard therapeutic choice for pediatric patients with end stage liver disease. Several diseases cause hepatic failure, and they can be treated with liver transplantation.
Cholestatic and metabolic diseases are the most common specific indications, and represent the indication of more than 90% of the transplantation performed.
Other pathological conditions that do not evolve in hepatic failure may be indications for liver transplantation. These are:
1.	Nonprogressive liver disease with morbidity higher than liver transplantation;
2.	Liver-based metabolic disease;
3.	Liver disease secondary to cystic fibrosis;
4.	Hepatic malignancies.